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Aromasin 25mg is a drug that is used to treat the symptoms of breast cancer. Aromasin can be used alone or in conjunction with other medications. Aromasin is an anticancer drug known as an Aromatase Inhibitor. The usefulness and safety of aromasin 25mg in children remain uncertain.

Side Effects

Aromasin 25mg may cause the following adverse effects: 

• bursts of heat 
• joint discomfort weariness
•  headache 
• nausea 
• increased urge to eat 
• sleep problems (insomnia) 
• increased sweat

Aromasin (Exemestane) can cause significant side effects such as

•  a new or unusual bone aching 
• shortness of breath due to swelling in your hands or feet 
• sudden numbness or weakness in the arms or legs 
• a strong headache 
• vision, speech, or balance problems

Tell your doctor if you develop a side effect that worries you or does not go away.

Aromasin 25mg has a number of undesirable side effects. These are only a few examples. For further information, see your doctor or pharmacist. AROMASIN Tablets, which contain 25 mg of exemestane, are a steroidal aromatase inactivator. Exemestane is known chemically as 6-Methylenandrosta-1,4-diene-3,17-dione. Its molecular formula is C20H24O2. The active ingredient is a white to slightly yellow crystalline powder with a molecular weight of 296.41. Exemestane is soluble in N, N-dimethylformamide, methanol, and water, but in the latter it is essentially insoluble.

Inactive ingredients in each AROMASIN Tablet include mannitol, crospovidone, polysorbate 80, hypromellose, colloidal silicon dioxide, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, simethicone, polyethylene glycol 6000, sucrose, magnesium carbonate, titanium dioxide, methylparaben, and polyvinyl alcohol.

Aromasin’s Applications

• Adjuvant Treatment for Postmenopausal Women

AROMASIN is licensed for postmenopausal women with estrogen-receptor positive early breast cancer who have finished two to three years of tamoxifen and want to switch to AROMASIN for a total of five years of adjuvant hormonal treatment.

• In postmenopausal women with advanced breast cancer

Aromasin 25mg is used to treat advanced breast cancer in postmenopausal women whose condition has progressed following treatment with tamoxifen.

Dosage

 The recommended dose of AROMASIN (Exemestane) in early and advanced breast cancer is one 25 mg tablet once daily after a meal. If you believe your dose should be changed, consult with your doctor first before making any rash decisions. Take the medication as soon as possible, but skip the missed dose if your next dose is approaching. Do not take two doses at the same time. Have your prescription renewed before you run out of drugs. In the event of an overdose, get medical help as soon as possible.

Precautions

 Aromasin should not be used if you are allergic to exemestane, haven’t entered menopause, or are pregnant or expecting to get pregnant. Aromasin should not be used if you are pregnant. It has the potential to harm a kid in the womb. Consult your doctor before using this drug if you have liver or kidney issues, or if you haven’t entered menopause but are still having menstrual periods.

Use Aromasin 25mg on a regular basis to get the most out of it. Have your prescription renewed before you run out of drugs. You may need to take this medication for up to 5 years. Pay heed to what your doctor says. It’s possible that if you take this drug with hormone replacement treatment, it won’t work as well.

What is Aromasin?

Exemestane, which is also sold under the brand name Aromasin, is a treatment for breast cancer. It is a member of the aromatase inhibitors class of antiestrogens. Estrogen is needed for some breast cancers to grow. These cancers are known as ER-positive because they contain estrogen receptors.

Aromasin is a prescription drug used to treat breast cancer symptoms. Aromasin can be taken alone or in conjunction with other medications.Aromasin is a member of the Antineoplastics, Aromatase Inhibitor class of drugs.The safety and efficacy of Aromasin in children are unknown.

Women who have gone through menopause are prescribed this medication to treat certain types of breast cancer, such as hormone-receptor positive breast cancer. Exemestane can also be used to stop the cancer from coming back. Estrogen, a naturally occurring hormone, accelerates the growth of some types of breast cancer. Exemestane slows or stops the growth of these breast cancers by reducing the body’s production of estrogen. Exemestane is rarely used in women who are pregnant. Aromasin may be prescribed to you by your doctor if you have breast cancer.

A physician endorsed medication’s utilized in females* who have gone through menopause. In some cases, aromasin is used to treat the following conditions:

• Breast cancer early on. This indicates that the cancer only affects your breast.
• Breast cancer that is advanced. This indicates that the cancer has spread elsewhere in your body.

How does Aromasin Works?

Aromasin works by inhibiting the enzyme aromatase, which is responsible for the body’s conversion of androgen into small amounts of estrogen. Because of this, breast cancer cells that are hormone receptor-positive have less estrogen available to stimulate growth.

The maximum suppression of circulating estrogens after a single 25 mg dose of exemestane occurred two to three days later and lasted four to five days.

Do you need any prescription for buying Aromasin?

Aromasin may be prescribed to you by your doctor if you have breast cancer. It is a prescription medication for women* who have entered menopause. In some cases, aromasin is used to treat the following conditions: Breast cancer early on.

Where to buy Aromasin?

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When you should take Aromasin?

One 25-milligram (mg) tablet of Aromasin should be taken once daily after a meal. Arimidex should be taken once daily, with or without food, with one 1-mg tablet.

One 25-milligram (mg) tablet of Aromasin is typically taken once daily. The medication is taken with a meal. 

When you should not take Aromasin?

Aromasin should not be taken by women who are pregnant or about to become pregnant. It may harm a developing fetus or cause birth defects. If you are able to get pregnant because of this risk, your doctor will tell you to take a pregnancy test within seven days of starting Aromasin.

Taking exemestane for the recommended amount of time will depend on your particular circumstance. Exemestane is typically taken by primary breast cancer patients for five to ten years. After several years of taking the hormone therapy drug tamoxifen, some people start taking exemestane.

What are the benefits of taking Aromasin?

In postmenopausal women, aromasin lowers estrogen levels, which may slow the growth of certain types of breast tumors that require estrogen to grow. In postmenopausal women, aromasin is used to treat early and advanced breast cancer. Cancer that has not spread outside the breast is considered early breast cancer.

What are the side effects of taking Aromasin?

Aromasin, like most drugs, can have minor or serious side effects. Some of Aromasin’s more common side effects are outlined in the following lists. Some of the potential side effects aren’t on these lists.

Keep in mind that a drug’s side effects can be influenced by:

1) your age;

2) any other health issues you may have; and

3) any other medications you may be taking.

Your pharmacist or physician can provide you with additional information regarding Aromasin’s potential side effects. Additionally, they may provide suggestions for minimizing adverse effects.

Sporadic side effects:-

A brief list of Aromasin’s mild side effects is provided below. Talk to your doctor or pharmacist about any other mild side effects, or read the patient information for Aromasin.

The following are mild Aromasin side effects have been reported:

1) pain in the joints,

2) hair loss,

3) weight gain,

4) headache, and

5) nausea 

Many medications can cause mild side effects that go away in a few days or a few weeks. However, if they become bothersome, consult your pharmacist or doctor.

Negative effects:-

Although rare, aromasin can have serious side effects. If you experience serious side effects, you should immediately contact your doctor. However, if you think you are experiencing a medical emergency, you should call 911 or your local emergency number.

The following are serious adverse effects of Aromasin that have been reported:

1) high blood pressure;

2) depression;

3) bone loss, which can raise the risk of osteoporosis and fractures;

4) heart-related issues, such as heart failure, chest pain, or an attack; and

 5) an allergic reaction*

Focus on side effects:-

• Aching joints

Consuming Aromasin may result in joint and other body aches. Joint pain was a frequent side effect in studies of the drug used to treat breast cancer in its early stages.

What might assist?:-

Talk to your doctor if you experience joint, muscle, or body aches while taking Aromasin. They might be able to suggest ways to deal with these side effects.

• Hair fall

Aromasin may lead to hair thinning. When the drug was used to treat early or advanced breast cancer, this was a frequent side effect that was observed in studies. Aromasin reduces estrogen levels, which is how it works. This can result in hair loss or thinning.

Aromasin may be prescribed by your physician following treatment with tamoxifen in some instances. Keep in mind that prolonged use of either medication can result in hair loss.

What might assist?:-

Talk to your doctor if you’re worried about losing your hair as a result of taking Aromasin. You can inquire about a medication known as minoxidil (Rogaine). Minoxidil was used to treat hair loss in breast cancer patients in one study, according to Trusted Source. Other options may also be available from your doctor.

• Gaining weight

Consuming Aromasin may make you gain weight. Aromasin was used to treat advanced breast cancer, and studies of the drug showed that it caused weight gain.

What might assist?:-

You should not stop taking Aromasin if you gain weight while taking it. Consult your doctor instead. During this treatment, they may suggest ways to assist you in maintaining a moderate weight.

What are the precautions you have to take if you are taking Aromasin?

1) Decreases in Bone Mineral Density (BMD) Over time, use of exemestane is associated with decrements in bone mineral density (BMD)….

2) Evaluation of Vitamin D.

3) Treatment with Estrogen-Containing Drugs

4) Errors in the laboratory…

5) Use in Women Before Menopause.

6) Toxicity to the fetus.

What is the recommended dose of Aromasin?

Dosage Recommendation:-

In cases of early and advanced breast cancer, one 25 mg tablet taken after a meal is the recommended dosage of AROMASIN.

1) adjuvant treatment of estrogen-receptor positive early breast cancer in postmenopausal women who have been on tamoxifen for two to three years and are switched to AROMASIN after five years of adjuvant hormonal therapy.

2) the treatment of advanced breast cancer in postmenopausal women whose disease has advanced after receiving tamoxifen.

Modifications to Doses:- 

Exemestane exposure is reduced when strong CYP 3A4 inducers are used concurrently. The recommended dose of AROMASIN for patients taking a strong CYP 3A4 inducer, such as rifampicin or phenytoin, is 50 mg once daily after a meal [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY].

What is the proper method of taking Aromasin?

Aromasin comes in the form of a tablet that must be swallowed once daily. It is best taken after a meal or with food. It might be helpful to take Aromasin every day after the same meal, like breakfast, so that it becomes a habit.

Exemestane comes in tablets form. Try to take it every day at the same time, preferably after eating.

When to take Aromasin?

Aromasin comes in the form of a tablet that must be swallowed once daily. It is best taken after a meal or with food. It might be helpful to take Aromasin every day after the same meal, like breakfast, so that it becomes a habit.

Does Aromasin interact with any other drug?

Your medications’ effects can be altered or you may experience more serious side effects if they interact with other medications. This document does not cover all possible drug interactions. Make a list of all the herbal products and prescription and nonprescription products you use with your doctor and pharmacist. Do not begin, stop, or alter the dosage of any medication without consulting your doctor.

The following products may interact with this medication: estrogens, including conjugated estrogens and ethinyl estradiol, estrogen blockers like anastrozole and tamoxifen, and tibolone.

What happen when someone overdose Aromasin?

If a person has taken an excessive amount of medication and is experiencing serious side effects like unconsciousness or difficulty breathing, they should dial 911 right away. If not, get in touch with a poison control center right away. In the United States, poison control centers can be reached at 1-800-222-1222. Canadians can get in touch with a provincial poison control center.

How do you feel when taking Aromasin?

Aromasin works by inhibiting the enzyme aromatase, which is responsible for the body’s conversion of androgen into small amounts of estrogen. This means that breast cancer cells that are hormone receptor positive have less estrogen available to stimulate growth.

Classification:

Molar Mass- 296.403 g/mol

CAS Id- 107868-30-4

Boiling Point- 453.7 C

Chembl Id- 1200374

Duration of Action- 4-5 days